1.
WHISK together buttermilk and hot pepper sauce in shallow baking dish. Add chicken pieces. Turn to coat. Cover and refrigerate 2 hours or up to 24 hours.
2.
STIR together flour, oregano, garlic powder, paprika, cayenne pepper, salt and black pepper in separate baking dish. Toss chicken pieces in seasoned flour, a few at a time, until well coated. Dip chicken in buttermilk, then coat again in flour mixture.
3.
POUR oil to a depth of 1-inch in large heavy skillet. Heat oil to 350ºF. Add chicken pieces in a single layer, skin side down. Fry about 4 minutes. Turn over. Fry the other side about 4 minutes. Turn again, frying a total of about 15 minutes until chicken is evenly golden brown and crisp and juices run clear. Remove cooked chicken from pan. Place on a paper towel lined plate to drain.